How Quickly Does Mebendazole Work? - Genericcures
Mebendazole usually starts working within a few hours after it is taken. While the medicine begins acting quickly, the complete removal of worms from the body may take a few days. Mebendazole works by blocking the worms’ ability to absorb glucose, which they need to survive. Without this energy source, the worms die slowly and are eventually expelled naturally through stool.
In many cases, especially for pinworms, symptoms like itching around the anus begin to improve within 24 to 48 hours. For larger or more deeply rooted infestations, such as roundworms or hookworms, it may take 2 to 3 days for the medication to fully eliminate the worms. However, even after the worms are killed, your body might take additional time to completely flush them out.
It is important to note that Mebendazole does not kill worm eggs, so doctors often recommend a second dose after 2 to 3 weeks to prevent reinfection. This second treatment ensures that any newly hatched worms are also removed from the body.
You don’t need to take Mebendazole with food, but taking it with a meal may help improve absorption. It’s also helpful to practice good hygiene—wash hands regularly, clean bedding, and avoid sharing towels—to prevent the spread or return of the infection.
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