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How Nitazoxanide Works To Treat Worm Infections?

Asked by drelizabethblackburn at 5:30am on Nov 26 2024

Nitazoxanide treats worm infections by interfering with the energy metabolism of parasites. It inhibits an enzyme called pyruvate:ferredoxin oxidoreductase (PFOR), which is essential for anaerobic energy production in parasites. This disruption halts the parasite's ability to generate energy, impairing its survival and replication. Nitazoxanide's broad-spectrum action is effective against various intestinal worms and protozoa, including Giardia and Cryptosporidium. Additionally, it modulates the immune response, enhancing the body's ability to combat infections. By targeting vital metabolic pathways unique to parasites, nitazoxanide 500mg effectively clears infections without significantly affecting human cells, making it a valuable antiparasitic medication.

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