How Fosfomycin Works Against Resistant Bacteria
Fosfomycin is a unique antibiotic known for its ability to treat infections caused by resistant bacteria, particularly in urinary tract infections (UTIs). It works by inhibiting an enzyme called MurA, which is essential for bacterial cell wall synthesis. Without this enzyme, bacteria cannot build their protective cell walls, leading to their death. Fosfomycin's unique mechanism of action makes it effective against drug-resistant strains of bacteria, including ESBL-producing E. coli and other multidrug-resistant pathogens. Additionally, its broad spectrum and ability to penetrate tissues make it a valuable tool in combating infections that are resistant to conventional antibiotics.